Cross-Reactivity in Drug Hypersensitivity Reactions to Sulfasalazine and Sulfamethoxazole
International Archives of Allergy and Immunology, 04/28/2010
Zawodniak A et al. – Te authors demonstrate that in the case of sulfamethoxazole and sulfasalazine, cross–reactivity is dependent on chemical features rather than the indication of the drugs. Therefore, patients with hypersensitivity to sulfasalazine or sulfamethoxazole should be specifically advised to avoid both drugs.