Cross-Reactivity in Drug Hypersensitivity Reactions to Sulfasalazine and Sulfamethoxazole

International Archives of Allergy and Immunology, 04/28/2010

Te authors demonstrate that in the case of sulfamethoxazole and sulfasalazine, cross–reactivity is dependent on chemical features rather than the indication of the drugs. Therefore, patients with hypersensitivity to sulfasalazine or sulfamethoxazole should be specifically advised to avoid both drugs.

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