Allergy/Imm Medical News about transient hypogammaglobulinemia of infancy

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Impaired specific antibody response and increased B-cell population in transient hypogammaglobulinemia of infancy
Annals of Allergy, Asthma, and Immunology, 11/23/06

Dorsey, Morna J., et al. - Transient hypogammaglobulinemia of infancy (THI) is a heterogeneous disorder with poorly understood pathophysiology...Conclusions: THI is associated with a number of immunologic abnormalities beyond just hypogammaglobulinemia. These abnormalities include impaired specific antibody responses and increased proportions of CD19+ B cells and may be suggestive of particular immunologic mechanisms that result in hypogammaglobulinemia

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