Enterohemorrhagic Escherichia coli O157:H7 Shiga Toxins Inhibit Interferon-gamma Mediated Cellular Activation Infection and Immunity, 05/10/2012

Ho NK et al. – The authors conclude that while other factors are likely involved in the suppression of IFNγ–mediated Stat–1 tyrosine phosphorylation, E. coli–derived Shiga toxins represent a novel mechanism by which Enterohemorrhagic Escherichia coli (EHEC) evades the host immune system.

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