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Age at onset and gender distribution of systemic lupus erythematosus, polymyositis/dermatomyositis, and systemic sclerosis in Japan
Modern Rheumatology, 08/21/2012
Clinical Article
Ohta A et al. – The basic descriptive epidemiological characteristics of systemic lupus erythematosus, polymyositis/dermatomyositis, and systemic sclerosis in Japan, such as gender distribution, present age, and age at onset, were surveyed nationwide for fiscal 2007. It was found that these characteristics were similar to those in Western populations. The authors' finding provides new information on the natural history of disease development.
Methods- The authors used epidemiological information on 21,405, 6,327, and 10,058 patients with SLE, PM/DM, and SSc, respectively, in a Japanese nationwide registration database of patients with intractable diseases.
- All three diseases occur predominantly in women, with the female–to–male ratio being 8.2:1, 2.6:1, and 7.7:1 for SLE, PM/DM, and SSc, respectively.
- The most susceptible age for SLE is 15–44 and 20–39 years for males and females, respectively.
- For PM/DM it is 45–64 and 40–64 years and for SSc, 50–69 and 40–59 for men and women, respectively.
