Synergistic effect of Tim4 and MFG-E8 null mutations on the development of autoimmunity
International Immunology, 06/22/2012
Miyanishi M et al. – The results suggest that the double deficiency of Tim4 and Milk Fat Globule EGF Factor VIII (MFG–E8), phosphatidylserine–binding proteins, can trigger autoimmunity and that TNFα and type I IFN regulate reciprocally the development of autoimmune disease.



