Humoral and Cellular Capsid-Specific Immune Responses to Adeno-Associated Virus Type 1 in Randomized Healthy Donors
The Journal of Immunology, 06/08/2012
Veron P et al. – The new data raise the question of prescreening patients not only for the humoral response, but also for the cellular response. Clearly, a better understanding of the natural immunology of adeno–associated virus (AAV) serotypes will allow us to improve AAV gene therapy and make it an efficient treatment for genetic disease.