Reassessment of Immune Correlates in Human Visceral Leishmaniasis as Defined by Cytokine Release in Whole Blood
Clinical and Vaccine Immunology, 05/30/2012
Singh OP et al. –The findings do not support a severe Th1 response defect in kala–azar. Importantly, only the patients with active visceral leishmaniasis (VL) also produced IL–10, which in conjunction with IFN–γ better reflects the immune responses that distinguish individuals with active disease from cured or subclinically infected, immune individuals.