Double negative Treg cells promote nonmyeloablative bone marrow chimerism by inducing T-cell clonal deletion and suppressing NK cell function
European Journal of Immunology, 05/15/2012
Su Y et al. – The results suggest that adoptive transfer of double negative(DN)Treg cells can control both adoptive and innate immunities and promote stable–mixed chimerism and donor–specific tolerance in the irradiation–free regimen.



