Urinary endothelin-1-like immunoreactivity excretion in Wilms tumor survivors

Pediatric Nephrology, 04/24/2012

According to the authors' results, urinary endothelin (ET)–1–like Immunoreactivity (uET–1 L) seems to be a marker of glomerular injury in patients with renal mass loss revealing renal overload condition. The uET–1 L role in renal damage progression and hemodynamic glomerular worsening in nephrectomized patients should be proven by prospective long–term follow–up studies, even for potential ET–1 receptor antagonist therapeutic use.

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