Nebulized Antibiotics for the Treatment of Refractory Bacterial Chronic Rhinosinusitis
Annals of Pharmacotherapy, 06/23/2011
Woodhouse BM et al. – Based on current studies, use of nebulized antibiotics for refractory Chronic rhinosinusitis (CRS) cannot be recommended at this time. Although supportive evidence is limited, nebulized antibiotics appear to improve rhinosinusitis symptoms in some patients with minimal adverse effects. With further studies, culture–directed nebulized antibiotic therapy may be a treatment option in patients with CRS refractory to conventional treatments.