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IL-33 promotes DC development in BM culture by triggering GM-CSF production
European Journal of Immunology, 11/10/09
Mayuzumi N et al. – With regard to the cellular source, IL–33–dependent GM–CSF production was observed exclusively within the CD45+/Fc[epsilon]RI+ BM population. Not only do our results reinforce the notion that GM–CSF serves as a primary DC growth factor, but they also reveal a previously unrecognized mechanism supporting DC development.
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