Allergy/Imm Medical News about blood-brain barrier

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Receptor-mediated therapeutic transport across the blood-brain barrier
Immunotherapy, 11/06/09

Wang YY et al. – After the BBB–targeting vector–therapeutic conjugates have crossed the BBB, there may still be a need to target them to a specific population of cells in the brain. This review will focus on two major aspects of RMT brain drug delivery: new advances of existing RMT systems and development of new BBB transport vectors and specific RMT targets.

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Measurement of brain perfusion, blood volume, and blood-brain barrier permeability, using dynamic contrast-enhanced T1-weighted MRI at 3 tesla
Magnetic Resonance in Medicine, 10/06/09 Relevance Score: 65%

A Pilot Study to Assess the Efficacy of Tariquidar to Inhibit P-glycoprotein at the Human Blood–Brain Barrier with (R)-11C-Verapamil and PET
The Journal of Nuclear Medicine, 11/17/09 Relevance Score: 64%

Reference Tissue Models and Blood–Brain Barrier Disruption: Lessons from (R)-[11C]PK11195 in Traumatic Brain Injury
The Journal of Nuclear Medicine, 11/17/09 Relevance Score: 64%

Evolving role of laminin receptors in microbial pathogenesis and therapeutics of CNS infection
Future Microbiology, 10/16/09 Relevance Score: 64%

The Blood-Brain Barrier Thyroxine Transporter Organic Anion-Transporting Polypeptide 1c1 Displays Atypical Transport Kinetics
Endocrinology, 10/14/09 Relevance Score: 64%