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Regulatory T Cell (Treg) Subsets Return in Patients with Refractory Lupus following Stem Cell Transplantation, and TGF-[beta]-Producing CD8+ Treg Cells Are Associated with Immunological Remission of Lupus
Journal of Immunology, 11/10/09
Zhang L et al. – Unlike conventional drug therapy, hemopoietic stem cell transplantation generates a newly differentiated population of LAPhighCD103high CD8TGF–? Treg cells, which repairs the Treg deficiency in human lupus to maintain patients in true immunological remission.
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