Allergy/Imm Medical News about NK alloreactivity

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Rapid, flow cytometric assay for NK alloreactivity reveals exceptions to rules governing alloreactivity
Biology of Blood and Marrow Transplantation, 11/05/09

De Santis D et al. – The percentage of alloreactive NK cells varied greatly between individuals and was easily estimated by the CD107a assay. For each epitope (C1, C2, Bw4), donors were found who did not have alloreactivity although alloreactivity was predicted by the current rules thought to govern alloreactivity. The data emphasize the importance of demonstrating alloreactivity in a functional assay.

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Effect of missing killer-immunoglobulin-like receptor ligand in recipients undergoing HLA full matched, non-T-depleted sibling donor transplantation: a single institution experience of 151 Asian patients
Bone Marrow Transplantation, 11/12/09 Relevance Score: 65%

The Role of Missing Killer-Cell Ig-like Receptor (KIR) Ligands in T Cell Replete Peripheral Blood Stem Cell Transplantation from HLA-Identical Siblings
Biology of Blood and Marrow Transplantation, 10/29/09 Relevance Score: 64%

Prognostic factors for mature natural killer (NK) cell neoplasms: aggressive NK cell leukemia and extranodal NK cell lymphoma, nasal type
Annals of Oncology, 10/29/09 Relevance Score: 47%

Functional Expression of Formyl Peptide Receptor Family in Human NK Cells
Journal of Immunology, 10/23/09 Relevance Score: 45%

Impaired Plasmacytoid Dendritic Cell (PDC)-NK Cell Activity in Viremic Human Immunodeficiency Virus Infection Attributable to Impairments in both PDC and NK Cell Function
Journal of Virology, 10/19/09 Relevance Score: 45%