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Value of eight-amino-acid matches in predicting the allergenicity status of proteins: an empirical bioinformatic investigation
Clinical and Molecular Allergy , 10/30/09
Herman RA et al. – The authors found that the allergen–sequence pairs only sharing 8–amino–acid identity, but not >35% identity over 80 amino acids, were unlikely to be cross reactive allergens. Thus, the common search for 8–amino–acid identity between novel proteins and known allergens appears to be of little additional value in assessing the potential allergenicity of novel proteins.
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