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Plasmodium falciparum infection of the placenta impacts on the T helper type 1 (Th1)/Th2 balance of neonatal T cells through CD4+CD25+ forkhead box P3+ regulatory T cells and interleukin-10
Clinical and Experimental Immunology, 11/04/09
Bisseye C et al. – Similar effects were observed by adding an antibody that blocks IL–10 function. These results suggest that the impact of P. falciparum infection on Th1 differentiation of neonatal T cells can be ascribed to regulatory T cells through production of IL–10.
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