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See Latest ArticlesThe inhibitory receptor LILRB4 (ILT3) modulates antigen presenting cell phenotype and, along with LILRB2 (ILT4), is upregulated in response to Salmonella infection
BMC Immunology, 10/29/09
Brown DP et al. – The authors' results indicate that the inhibitory effects of LILRB4 do not result from a failure to upregulate co–stimulatory proteins. In addition to the high level expression that can render antigen presenting cells tolerogenic, there may be a role for lower level expression and activity of LILRB2 and LILRB4 in response to TLR signalling during an immune response to bacterial infection.
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