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Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone
Journal of Experimental Medicine, 10/30/09
Nastruzzi C et al. – The effect was associated with restoration of systemic immune tolerance and detection of functional pancreatic islets that consisted of glucose–responsive and insulin–secreting cells. Curative effects by SC were strictly dependent on efficient tryptophan metabolism in the xenografts, leading to TGF–beta–dependent emergence of autoantigen–specific regulatory T cells and recovery of beta cell function in the diabetic recipients.
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The Endocrinologist, 11/16/09
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Obesity Reviews, 11/02/09
Clinical Applications of Diabetes Antibody Testing
Journal of Clinical Endocrinology and Metabolism, 11/02/09
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