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Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2)
Journal of Experimental Medicine, 11/03/09
Fogelstrand P et al. – The studies establish the importance of CD98hc in VSMC proliferation and survival. Furthermore, loss of CD98hc was selectively deleterious to activated VSMCs while sparing resident quiescent VSMCs, suggesting that activated VSMCs are physiologically dependent on CD98hc, and hence, CD98hc is a potential therapeutic target in vaso–occlusive disorders.
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Today in Cardiovascular/Pulm...keeping you current
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Role of adenoids and adenoiditis in children with allergy and otitis media
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Montelukast in the treatment of asthma and beyond
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