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See Latest ArticlesId2-, ROR{gamma}t-, and LT{beta}R-independent initiation of lymphoid organogenesis in ocular immunity
Journal of Experimental Medicine, 11/03/09
Nagatake T et al. – Initiation of TALT genesis began postnatally; it occurred even in germ–free conditions and was independent of signaling through organogenesis regulators, including inhibitor of DNA binding/differentiation 2, retinoic acid–related orphan receptor [gamma]t, lymphotoxin (LT) [alpha]1?2–LT?R, and lymphoid chemokines (CCL19, CCL21, and CXCL13). Thus, TALT shares immunological features with MALT but has a distinct tissue genesis mechanism and plays a key role in ocular immunity.
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