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See Latest ArticlesTGF-beta inhibits IL-1beta-activated PAR-2 expression through multiple pathways in human primary synovial cells
BMC: Journal of Biomedical Science, 10/26/09
Tsai SH et al. – TGF–could prevent OA from progression with the anabolic ability to induce CTGF production to maintain extracellular matrix (ECM) integrity and to down regulate PAR–2 expression, and the anti–catabolic ability to induce Tissue inhibitors of metalloproteinase–3 (TIMP–3) production to inhibit MMPs leading to avoid PAR–2 over–expression. Because IL–1–induced PAR–2 expressed in hPSCs might play a significantly important role in early phase of OA, PAR–2 repression by exogenous TGF– or other agents might be an ideal therapeutic target to prevent OA from progression.
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Today in Basic Science/Genetics...keeping you current
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Genetics: Schizophrenia
Canadian Family Physician, 12/16/09
Association between SOD2 T-9C and MTHFR C677T polymorphisms and longevity: a study in Jordanian population
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Today in Basic Science/Genetics...keeping you current
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Genetics: Schizophrenia
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Nitric oxide and coronary vascular endothelium adaptations in hypertension
Vascular Health and Risk Management, 12/16/09
The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs
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Today in Rheumatology...keeping you current
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Taking the stress out of managing gout
Canadian Family Physician, 12/16/09
Predictors of Damage and Survival in Patients with Wegener's Granulomatosis: Analysis of 50 Patients
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Pharmacology & Therapeutics, 12/16/09
Today in Rheumatology...keeping you current
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Taking the stress out of managing gout
Canadian Family Physician, 12/16/09
The immunobiology of viral arthritides
Pharmacology & Therapeutics, 12/16/09
Lymphatic and blood vessels in scleroderma skin, a morphometric analysis
Human Pathology, 12/16/09
Today in Rheumatology...keeping you current
Receive free subspecialty "5-minute updates" via email
Taking the stress out of managing gout
Canadian Family Physician, 12/16/09
Lymphatic and blood vessels in scleroderma skin, a morphometric analysis
Human Pathology, 12/16/09
Predictors of Damage and Survival in Patients with Wegener's Granulomatosis: Analysis of 50 Patients
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