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European population substructure correlates with systemic lupus erythematosus endophenotypes in North Americans of European descent
Genes and Immunity, 10/26/09
Richman IB et al. – Homogeneous clusters of cases defined by multiple PCs demonstrated stronger phenotypic associations. Genetic ancestry may contribute to the development of SLE endophenotypes and should be accounted for in genetic studies of disease characteristics.
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