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See Latest ArticlesOligomerized TICAM-1 (TRIF) in the cytoplasm recruits nuclear BS69 to enhance NF-[kappa]B activation and type I IFN induction
European Journal of Immunology, 10/26/09
Takaki H et al. – The results, together with a recent report showing the negative regulatory properties of BS69 in NF–kB activation by EBV–derived latent membrane protein 1, suggest that BS69 harbors dual modes of cytoplasmic NF–kB regulation, positively in the TICAM–1 pathway and negatively in the latent membrane protein 1 pathway.
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