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See Latest ArticlesLymph node tumor metastases: more susceptible than primary tumors to CD8+ T-cell immune destruction
Trends in Immunology, 10/21/09
Contassot E et al. – The authors discuss here how a non–hematopoietic cell can efficiently prime CD8+ T cells by direct presentation in lymph nodes. Such a T–cell activation pathway is likely to be of importance for the control of cancer metastases that use the lymphatic system to spread.
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