Allergy/Imm Medical News about Histamine Antagonists

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Otitis media and antihistamines
Current Allergy and Asthma Reports, 10/22/09

Goodrich T et al. – The efficacy of antihistamines in the treatment of OME/AOM has been thoroughly refuted in the literature during the past three decades. However, most studies to date have used first–generation antihistamines with or without decongestants. The authors propose that second–generation antihistamines may have increased efficacy in the treatment of OME/AOM because of their greater selectivity for histamine receptors and lack of anti–cholinergic activity.

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The Histamine H4 Receptor Mediates Inflammation and Pruritus in Th2-Dependent Dermal Inflammation
Journal of Investigative Dermatology, 11/13/09 Relevance Score: 64%

Histamine Stimulates Interleukin-6 Production through Histamine H1 Receptors in Human Amnion Cells
Gynecologic and Obstetric Investigation, 11/17/09 Relevance Score: 45%

Sinus aspergilloma in rheumatoid arthritis before or during tumor necrosis factor-alpha antagonist therapy
Arthritis Research & Therapy, 11/11/09 Relevance Score: 45%

Death temporally related to the use of a beta adrenergic receptor antagonist in cocaine associated myocardial infarction
Journal of Medical Toxicology, 11/10/09 Relevance Score: 45%

Early and short follicular gonadotropin-releasing hormone antagonist supplementation improves the meiotic status and competence of retrieved oocytes in in vitro fertilization-embryo transfer cycles
Fertility and Sterility, 10/12/09 Relevance Score: 45%