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The need to identify myeloid dendritic cell progenitors in human blood
Trends in Immunology, 10/27/09
Mortellaro A et al. – Access to lymphoid tissues for human DC isolation is severely limited and researchers have resorted to the use of in vitro derivation systems in attempts to understand DC development, which may result in misleading conclusions. The identification of a human DC progenitor in blood would greatly enhance the understanding of DC homeostasis and their role in pathogenesis.
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