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Induction of Treg by monocyte-derived DC modulated by vitamin D3 or dexamethasone: Differential role for PD-L1
European Journal of Immunology, 10/26/09

Unger WWJ et al. – The findings demonstrate that both VD3– and Dex–DC possess durable but differential tolerogenic features, acting via different mechanisms. Both are potentially useful to specifically down–regulate unwanted immune responses and induce immune tolerance. These modulated DC appear suitable as adjuvant in antigen–specific clinical vaccination intervention strategies.

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