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Successful hematopoietic stem cell transplantation in two children with X-linked chronic granulomatous disease from their unaffected HLA-identical siblings selected using pre-implantation genetic diagnosis combined with HLA-typing
Biology of Blood and Marrow Transplantation, 10/22/09
Goussetis E et al. – The present report demonstrates that HSCT with HLA–matched sibling donors created by PGD/HLA typing of in vitro fertilized embryos is a realistic therapeutic option and should be presented as such to families with children who need a non–urgent HSCT but lack an HLA–genoidentical donor.
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