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Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A
Retrovirology, 10/15/09

Hoque M et al. – At clinically relevant concentrations, two widely used drugs blocked HIV–1 replication ex vivo. They specifically inhibited expression from the HIV–1 promoter at the level of transcription initiation. Both drugs interfered with the hydroxylation step in the hypusine modification of eIF5A. These results have profound implications for the potential therapeutic use of these drugs as antiretrovirals and for the development of optimized analogs.

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Prevalence and Correlates of Elevated Body Mass Index among HIV-Positive and HIV-Negative Women in the Womens Interagency HIV Study
AIDS Patient Care and STDs, 11/19/09 Relevance Score: 95%

Effectiveness of Increasing Emergency Department Patients' Self-perceived Risk for Being Human Immunodeficiency Virus (HIV) Infected Through Audio Computer Self-interview–based Feedback About Reported HIV Risk Behaviors
Academic Emergency Medicine, 11/11/09 Relevance Score: 95%

HIV-Specific Health Care Utilization and Mortality among Tuberculosis/HIV Coinfected Persons
AIDS Patient Care and STDs, 10/06/09 Relevance Score: 95%

Mediators of HIV-related stigma and risk behavior in HIV infected young women
AIDS Care, 11/12/09 Relevance Score: 94%

Sperm May Play Leading Role In Spreading HIV
ScienceDaily, 10/27/09 Relevance Score: 94%