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Increased Ectonucleotidase Expression and Activity in Regulatory T Cells of Patients with Head and Neck Cancer
Clinical Cancer Research, 10/19/09
Mandapathil M et al. – CD39+ Treg frequency and adenosine–mediated suppression are significantly increased in HNSCC patients. The adenosinergic pathway is involved in Treg–mediated immunosuppression in cancer and its attenuation could be a promising immunotherapeutic strategy for patients with HNSCC.
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Today in Hematology/Oncology...keeping you current
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