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Herway C et al. – Interleukin–23 and IL–12 share a common p40 subunit and no inhibition of IL–12 was apparent. It appeared that a component of mid–trimester amniotic fluid specifically interacts with the p19 subunit unique to IL–23. Mid–trimester amniotic fluid reactivity with IL–23 may be a mechanism to limit intra–amniotic neutrophil–derived inflammation.


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