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See Latest ArticlesHIV-1 neutralization by monoclonal antibody against conserved region 2 and patterns of epitope exposure on the surface of native viruses
Journal of Immune Based Therapies and Vaccines, 10/14/09
Sreepian A et al. – This study demonstrates the cross–clade neutralizing activity of a MAb directed against an epitope located in the C2 region of the HIV–1 env and highlights differences in the exposure of antigenic epitopes on the surface of various HIV–1 subtypes. The epitope for this newly identified neutralizing MAb made against a subtype CRF01_AE peptide is particularly exposed in subtype C viral isolates.
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