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Greener m – Eczema is one of the most common dermatological diseases and the number of cases has risen markedly over recent years. Emollients and topical steroids are the first–line treatments for mild–to–moderate eczema. Emollients reduce itching and irritation, rehydrate skin, protect against further drying and may reduce the need for topical steroids by up to 50%. Some eczema patients respond adequately to emollients alone. However, patients with moderate–to–severe eczema, and those who do not respond to first–line treatments, might require second–line therapies, such as calcineurin inhibitors, ultraviolet phototherapy and systemic drugs. The inflammatory changes that cause eczema may persist between flares. Therefore, patients with mild–to–moderate eczema can now apply tacrolimus proactively to skin areas prone to flare and that previously responded to the calcineurin inhibitor to reduce the frequency and severity of exacerbations.

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