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Interleukin 17 Is Not Required for Autoimmune-Mediated Pathologic Damage during Chronic Graft-versus-Host Disease
Biology of Blood and Marrow Transplantation, 10/07/09
Chen X et al. – TH1 cells and other proinflammatory cytokines are fully competent to promote autoimmune–mediated tissue damage. Thus, the selective targeting of IL–17 may not be a viable clinical strategy for preventing the autoimmune manifestations that develop during cGVHD.
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