Allergy/Imm Medical News about Antitumor Reactivity

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Platelet-Derived Transforming Growth Factor-beta Down-Regulates NKG2D Thereby Inhibiting Natural Killer Cell Antitumor Reactivity
Cancer Research, 10/06/09

Kopp H–G et al. – Natural killer (NK) cells play an important role in cancer immunosurveillance and may prevent tumor progression and metastasis due to their ability to mediate direct cellular cytotoxicity and by releasing immunoregulatory cytokines, which shape adaptive immune responses. The data elucidate the molecular basis of the previously described influence of platelets on NK cell antitumor reactivity and suggest that therapeutic intervention in tumor cell–platelet interaction and the resulting TGF–beta release by platelets may serve to enhance antitumor immunity.

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IgE cross-reactivity between Ascaris and domestic mite allergens: the role of tropomyosin and the nematode polyprotein ABA-1
Allergy, 10/22/09 Relevance Score: 43%

Postprandial Vascular Reactivity in Obese and Normal Weight Young Adults
Obesity, 10/19/09 Relevance Score: 43%

Stress and decision-making in humans: Performance is related to cortisol reactivity, albeit differently in men and women
Psychoneuroendocrinology, 10/22/09 Relevance Score: 42%

Children's patterns of emotional reactivity to conflict as explanatory mechanisms in links between interpartner aggression and child physiological functioning
Journal of Child Psychology and Psychiatry and Allied Disciplines, 10/20/09 Relevance Score: 42%

Learning the lessons of antitumour necrosis factor therapy-associated psoriasis
Canadian Journal of Gastroenterology, 10/13/09 Relevance Score: 42%