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Antiglioma Immunological Memory in Response to Conditional Cytotoxic/Immune-Stimulatory Gene Therapy: Humoral and Cellular Immunity Lead to Tumor Regression
Clinical Cancer Research, 10/06/09

Muhammad AKMG et al. – Treatment with Ad–Flt3L + Ad–TK triggered systemic anti–glioblastoma multiforme cellular and humoral immune responses, and anti–glioblastoma multiforme immunological memory. Release of the chromatin–binding protein high mobility group box 1 could be used as a noninvasive biomarker of therapeutic efficacy for glioblastoma multiforme. The robust treatment efficacy lends further support to its implementation in a phase I clinical trial.

Today in Basic Science/Genetics...keeping you current

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Innate immune responses to influenza A H5N1: friend or foe
Trends in Immunology, 10/30/09

Mesenchymal Stem Cell Homing Capacity
Transplantation, 10/29/09

Evolution of Bone Disease at 2 Years After Transplantation: A Single-Center Study
Transplantation Proceedings, 11/06/09

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Today in Hematology/Oncology...keeping you current

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Factors affecting neutrophil recovery after autologous bone marrow-derived stem cell transplantation in patients with acute myeloid leukemia
Transplantation Proceedings, 11/23/09

Intratumoral Cytokines and Tumor Cell Biology Determine Spontaneous Breast Cancer–Specific Immune Responses and Their Correlation to Prognosis
Cancer Research, 11/03/09

Randomized phase III trial on gemcitabine versus mytomicin in recurrent superficial bladder cancer: Evaluation of efficacy and tolerance
Journal of Clinical Oncology, 10/23/09

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