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The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions
Trends in Immunology, 10/09/09
Clark GJ et al. – This review clarifies the occasionally confusing usage of nomenclature for the CD300 family and summarizes our current understanding of their genomics, expression and function. Their ability to fine tune leukocyte function and immune responses highlights several potential options to exploit the CD300 molecules as therapeutic targets in chronic inflammatory diseases, allergy and other disease states.
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