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Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage associated P. falciparum protein PFF0165c
Infection and Immunity, 10/19/09
Olugbile S et al. – The immunological properties of P27A together with its low polymorphism and association with clinical protection from malaria in human warrant its further development as a malaria vaccine candidate.
G Corradin, 11/05/09
| This is the first example of a candidate malaria vaccine identified by searching the malaria genome for red blood cell associated malaria proteins containing simple protein structural motifs and further down selected through a stringent selection procedure. The overall approach is very rapid and took 1-2 years from discovery to the clinics. |
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