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Response to Nonnucleoside Reverse Transcriptase Inhibitor-Based Therapy in HIV-Infected Children with Perinatal Exposure to Single-Dose Nevirapine
AIDS Research and Human Retroviruses, 10/15/09
Musiime V et al. – HIV–infected children with perinatal exposure to single–dose nevirapine are less likely to achieve short–term virologic suppression when started on an NNRTI–containing regimen, when compared to those who were not exposed to it, probably because the exposure predisposes them to developing NNRTI resistance mutations.
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