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Dapsone hypersensitivity syndrome with circulating 190-kDa and 230-kDa autoantibodies
Clinical and Experimental Dermatology, 10/07/09
Lee JB et al. – Dapsone has potent anti–inflammatory effects, and is used in the treatment of leprosy, cutaneous vasculitis, neutrophilic dermatoses, and dermatitis herpetiformis and other blistering disorders. However, it may cause severe adverse reactions such as hypersensitivity syndrome, which is characterized by fever, skin rash, hepatitis and lymphadenopathy.
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