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See Latest ArticlesBiochemical analysis of CTLA-4 immunoreactive material from human blood
BMC Immunology, 09/24/09
Tector M et al. – The authors have identified molecules in blood that are recognized by CTLA–4 specific antibodies but also exhibit properties of immunoglobulins. The data indicates that what has been called sCTLA–4 is not a direct product of the CTLA–4 gene, and that the CTLA–4 protein is not part of this molecule. These results may explain why the relationship of sCTLA–4 to immune system activity has been difficult to elucidate.
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