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See Latest ArticlesCirculating subsets and CD4 + CD25 + regulatory T cell function in chronic inflammatory demyelinating polyradiculoneuropathy
Autoimmunity, 09/21/09
Sanvito L et al. – This study shows increased circulating monocytes and reduced NK cells in CIDP. Although Treg frequency was not altered, we confirm that Tregs display a defect of suppressive function. Myelin protein peptides were not the target of the altered peripheral regulation of the immune response. The mechanisms of peripheral immune tolerance in CIDP and their relevance to the pathogenesis deserve further exploration.
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