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An additional ORF on meloe cDNA encodes a new melanoma antigen, MELOE-2, recognized by melanoma-specific T cells in the HLA-A2 context
Cancer Immunology, Immunotherapy, 09/23/09
Godet Y et al. – The results demonstrate that translation of meloe transcript in melanoma cells can produce at least two immunogenic polypeptides, MELOE–1 and MELOE–2, from two distinct ORFs that could be relevant target for melanoma immunotherapy.
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