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See Latest ArticlesEngineered anti-CD20 antibodies with enhanced complement-activating capacity mediate potent anti-lymphoma activity
Cancer Science, 09/28/09
Natsume A et al. – These findings suggest that CDC enhancement, both alone and in combination with ADCC enhancement, increases the anti–lymphoma activity of anti–CD20 antibodies irrespective of individual differences in effector functions, and renders current anti–CD20 therapy capable of overcoming the potential resistance mechanisms.
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