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Montanheiro PA et al. – IL–4, IL–10, TNF–alpha and IL–12 p70 levels were not significantly increased on both groups of patients, as compared with controls. The major finding of this study is that IFN–gamma was an important cytokine for the HAM/TSP pathogenesis. Therefore, immune modulation of IFN–gamma may be critical to treat of HAM/TSP patients.


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