Allergy/Imm Medical News about Lymphomatoid Granulomatosis

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A Case of Pulmonary Lymphomatoid Granulomatosis Successfully Treated by Combination Chemotherapy with Rituximab
Chemotherapy, 09/14/09

Jung KH et al. – Lymphomatoid granulomatosis (LYG) is a rare angiocentric and angiodestructive lymphoproliferative disease characterized by Epstein–Barr virus–positive B cells admixed with reactive T cells. The authors report the case of a 70–year–old male patient with pulmonary LYG, who showed rapid remission of the disease after combination chemotherapy with rituximab.

Exclusive Author Commentary
Je Hyeong Kim, 09/17/09

Lymphomatoid granulomatosis (LYG) is a rare lymphoproliferative disease, considered as non-Hodgkin’s B cell neoplasm. Standard treatment is not yet established and rituximab has been recently reported with variable responses. The authors emphasized the effect of rituximab with combination chemotherapy in a 70-year-old male patient with pulmonary LYG, and suggested the potential role of FDG-PET in the diagnosis and evaluation of treatment response in the patient with LYG.

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