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Abnormal B-cell activation associated with TALL-1 over-expression and SOCS-1 suppression during chronic hepatitis C virus infection
Immunology, 09/11/09
Moorman J et al. – The findings suggest that TALL–1 over–expression and SOCS–1 suppression are associated with aberrant B–cell activation, providing a plausible basis for the B–cell clonal expansion underlying the lymphoproliferative disorders and autoimmune phenomena observed during chronic HCV infection.
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