Allergy/Imm Medical News about Pseudomonas aeruginosa

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A genome-wide study of Pseudomonas aeruginosa outer membrane protein immunogenicity using self-assembling protein microarrays
Infection and Immunity, 09/29/09

Montor WR et al. – From this study it was possible to identify 12 proteins that trigger an adaptive immune response in cystic fibrosis and acutely–infected patients, providing valuable information about which bacterial proteins are actually recognized by the immune system in vivo, during the natural course of infection. Their differential detection between patients and controls proved to be statistically significant. The study provides a list of potential candidates for the improvement of serological diagnostics and the development of vaccines.

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