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Hall JR et al. – GBM occurs at an increased frequency and younger age in the HIV population than in the general population. HIV itself is not found in glioma specimens, but the effect of HIV infection on reduced immune surveillance is thought to promote the development of these tumours. The approach to management of HIV–positive patients with GBM should be the same as the general population, using surgery, radiotherapy and chemotherapy. Survival of glioma patients with HIV is dictated by their tumour, not their HIV status.

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