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See Latest ArticlesAlternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes
European Journal of Immunology, 09/29/09
Jones DC et al. – In vitro assays suggested that soluble LILRB1 could block the interaction between membrane–associated LILRB1 and HLA–class I. Soluble LILRB1 may act as a dominant negative regulator of HLA–class I–mediated LILRB1 inhibition. Soluble isoforms of the other LILR may function in a comparable way.
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